A inteligibilidade da palavra em igrejas católicas, através de análises de carácter objectivo e subjectivo
Lencastre, Margarida Maria Mendes de Freitas de Queiroz e
1988-01-01
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There are a number of disadvantages with conventional tissue immunohistochemistry for accurate -localisation of claudin proteins. Traditionally, tissue cryopreservation or formaldehyde fixation with wax embedding is utilised prior to sectioning and antibody localisation. Wax embedding gives better morphological preservation than frozen tissue, but the required use of chemical cross-linking fixatives renders many antigens inaccessible to antibody binding or results in subsequent disruption of antibody localisation patterns due to the use of harsh antigen retrieval methods. Use of frozen or wax-embedded tissue also requires the cutting of relatively thick >6-μm sections, making the interrogation of serial sections very limited. The use of glycolmethacrylate (GMA) tissue embedding with fixation in acetone is compatible with epitope preser...
In this paper we review the Hamiltonian description of General Relativity using a double null foliation.We start by looking at the 2+2 version of geometrodynamics and show the role of the conformal 2-structure of the 2-metric in encoding (through the shear) the 2 gravitational degrees of freedom. In the second part of the paper we consider instead a canonical analysis of a double null 2+2 Hamiltonian description of General Relativity in terms of self-dual 2-forms and the associated SO(3) connection variables. The algebra of first class constraints is obtained and forms a Lie algebra that consists of two constraints that generate diffeomorphisms in the two surface, a constraint that generates diffeomorphisms along the null generators and a constraint that generates self-dual spin and boost transformations.
The Sexual Inhibition/Sexual Excitation Scales (SIS/SES) assess individual propensities to become sexually aroused and to inhibit arousal. Prior analyses of men's SIS/SES data (Janssen, Vorst, Finn, & Bancroft, 2002a) yielded one excitation factor (SES) and two inhibitory factors (SIS1/Threat of Performance Failure and SIS2/Threat of Performance Consequences). The current study utilized a dataset of 2,045 undergraduates (1,067 women and 978 men) to examine the psychometric properties of women's SIS/SES scores.
Women scored higher on sexual inhibition and lower on sexual excitation compared with men. The convergent/discriminant validity of women's SIS/SES scores globally resembled men's, but showed stronger associations with other sexuality − related measures and less pronounced relationships with measures of general behavioral approac...
Patients with multiple sclerosis (MS) may be at an increased risk of fracture owing to a greater risk of falling and decreased bone mineral density when compared with the general population. This study was designed to estimate the relative and absolute risk of fracture in patients with MS. We conducted a population-based cohort study using data from the UK General Practice Research Database linked to the National Hospital Registry (1997–2008). Incident MS patients (n = 5565) were matched 1:6 by year of birth, sex, and practice with patients without MS (controls). Cox proportional-hazards models were used to derive adjusted hazard ratios (HRs) for fracture associated with MS. Time-dependent adjustments were made for age, comorbidity, and drug use. Absolute 5- and 10-year risks of fracture were estimated for MS patients as a function of...
Summary Partial adherence in osteoporosis increases the
risk for fragility fracture and has considerable impact on
cost-effectiveness. This review highlights a number of
avenues for further research, such as improved definition
of thresholds of compliance and persistence, as well as gap
length, offset times, and fraction of benefit.
Introduction A number of economic models have been
developed to evaluate osteoporosis therapies and support
decisions regarding efficient allocation of health care
resources. Adherence to treatment is seldom incorporated
in these models, which may reduce their validity for
decision-making since adherence is poor in real-world
clinical practice.
Methods An ad hoc working group of the European Society
for Clinical and Economic Aspects of Osteoporosis and
Osteoarthritis met to review key issues concerning the
...
This paper deals with the identification of elastoplastic constitutive parameters from deformation fields measured over the surface of thin flat specimens with the grid method. The approach for recovering the constitutive parameters is the virtual fields method. A dedicated algorithm is used for deriving the distribution of the 2D stress components from the measured deformation fields. A state of plane stress is assumed. Guesses of the constitutive parameters are input in the algorithm and updated until the stresses satisfy the principle of virtual work in the least squares sense. The advantage of this approach is that it can handle very heterogeneous plastic flows and it is much faster than classical finite element model updating approaches. An experimental application is provided to demonstrate it. Six mild steel double-notched speci...
Skills training is a crucial mode of treatment in dialectical behavioral therapy (DBT; Linehan, 1993b), yet a psychometrically sound measure of DBT skills use does not exist. We adapted the Revised Ways of Coping Checklist (RWCCL; Vitaliano, Russo, Carr, Maiuro, & Becker, 1985) to create the DBT Ways of Coping Checklist (DBT-WCCL). Using factor analysis procedures, two subscales emerged: one assessing coping via DBT skills, the DBT Skills Subscale (DSS), and one assessing coping via dysfunctional means, the Dysfunctional Coping Subscale (DCS). Principal component, internal consistency, test-retest reliability, and content validity analyses suggested that the scale has good to excellent psychometric properties. In addition, the DSS successfully discriminated patients who received skills training during 4 months of treatment from patient...
