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Um künftig Zuchtmethoden etablieren zu können, behandelt die vorliegende Dissertation die drei essentiellen Schritte in der sexuellen Vermehrung von Korallen: Das Planulationsverhalten, die Ansiedlung sowie die ersten Jugendstadien wurden anhand von Modelarten in ex situ Populationen studiert. Die vorliegende Arbeit umfasst praktische, anwendungsorientierte und wichtige grundlagenwissenschaftliche Aspekte bezüglich der Fortpflanzungsökologie, als auch der Marikultur und Aquakultur von riffbildenden Steinkorallen. In der vorliegenden Dissertation wurden zahlreiche Techniken entwickelt, um die nötige Basis zu einer umfangreich ex situ Zucht zu bilden. Dies umfasst Transporttechniken für adulte Brutkolonien, Korallenlarven und Primärpolypen. Ferner wurden neuartige Siedlungssubstrate zur räumlichen Steuerung der Ansiedlung, sowie der eff...
Chorea is characterized by abnormal hyperkinetic movements which may be a clinical symptom in a wide array of neurological disorders. This report describes the case of a 7-year-old boy who developed a paroxysmal, right-sided hemichorea three weeks after a throat infection. In correlation to the clinical findings, the area of the left putamen presented with a minimal lesion in diffusion weighted Magnetic resonances imaging which was not further evident two weeks later. Corresponding flour deoxy glucose positron emisson tomograpy showed an increased glucose uptake of the left lentiform nucleus and left frontocentral cortex. Given the serological evidence of streptococcal infection as specific trigger, this case report illustrates not only the importance of neuroimaging data in the differential diagnosis of chorea but also the potential p...
MRI of the brain was performed on 56 children with bilateral spastic cerebral palsy (CP) at a mean age of 10.7 years. Specific pathology was found in 91 per cent; periventricular leukomalacia was present in 42 per cent of term- and 87 per cent of preterm-born children. Parasagittal subcorticocortical injury, multicystic encephalomalacia and basal ganglia lesions were identified in 16 per cent, in all but one associated with severe peri-/neonatal events at term or near term. Maldevelopment comprised 9 per cent, all but one found in term-born children. MRI morphology correlated strikingly with outcome. Periventricular leukomalacia was associated with more severe disability in term- than preterm-born children.
Pectenotoxins from marine dinoflagellates of the genus Dinophysis are rapidly hydrolyzed by many shellfish to give pectenotoxin-2 seco acid, which isomerizes to 7-epi-pectenotoxin-2 seco acid. Three series of fatty acid esters of pectenotoxin-2 seco acid (PTX-2 seco acid) and 7-epi-PTX-2 seco acid were detected by LC-MS analysis of extracts from blue mussels (Mytilus edulis) from Ireland. The locations of the fatty acid ester linkages were identified by a combination of LC-MSn in positive- and negative-ion modes, LC-MS analysis of the products from reaction of the esters with sodium periodate, and NMR analysis of purified samples of the two most abundant ester derivatives. The 37-O-acyl esters of PTX-2 seco acid were the most abundant, followed by the corresponding 11-O-acyl esters, accompanied by low levels of the 33-O-acyl esters. Th...
A cis-isomer of a C8-diol ester of okadaic acid (1) was isolated during large-scale purification of pectenotoxins (PTXs) from extracts of Dinophysis acuta collected from the west coast of South Island, New Zealand. The compound was identified by NMR spectroscopic and liquid chromatography-mass spectrometry (LC-MS) studies, and is the first reported cis-isomer of an okadaic acid C₈-diol-ester identified in Dinophysis. The more abundant trans-C₈-diol ester of okadaic acid (2) isolated from the same Dinophysis extract was rapidly hydrolyzed to okadaic acid in vitro by the supernatant from green-lipped mussel hepatopancreas.
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